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Henning Wittenburg Selected Research

Gallstones (Gallstone)

6/2013Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus.
5/2013Heap of stones: an unusual cause for biliary colic and elevated liver function tests.
11/2011Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts.
10/2010Hereditary liver disease: gallstones.
10/2009A variant of the SLC10A2 gene encoding the apical sodium-dependent bile acid transporter is a risk factor for gallstone disease.
7/2008Hepatic insulin resistance ties cholesterol gallstone formation and the metabolic syndrome.
1/2008Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans.
12/2006Cholesterol gallstone susceptibility loci: a mouse map, candidate gene evaluation, and guide to human LITH genes.
10/2006Susceptibility to cholesterol gallstone formation: evidence that LITH genes also encode immune-related factors.
8/2006QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.
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Henning Wittenburg Research Topics

Disease

17Gallstones (Gallstone)
06/2013 - 02/2002
7Cholelithiasis
06/2013 - 02/2002
3Chronic Pancreatitis
01/2012 - 01/2010
2Genetic Predisposition to Disease (Genetic Predisposition)
11/2014 - 09/2003
2Pancreatitis
01/2012 - 10/2010
1Deglutition Disorders (Dysphagia)
03/2016
1Mycoses (Diseases, Fungus)
03/2016
1Anastomotic Leak
11/2015
1Pulmonary Hypertension
11/2014
1Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis)
01/2012
1Cholangitis
10/2010
1Cholecystitis
10/2010
1Pain (Aches)
10/2010
1Sitosterolemia
02/2010
1Hematologic Diseases (Blood Diseases)
02/2010
1Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2008
1Insulin Resistance
07/2008
1Whipple Disease (Whipple's Disease)
06/2008
1Inflammation (Inflammations)
10/2006
1Calculi (Calculus)
10/2006
1Acute Necrotizing Pancreatitis
09/2006
1Flushing
09/2006
1Intestinal Fistula
04/2005
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
05/2003
1Body Weight (Weight, Body)
02/2002

Drug/Important Bio-Agent (IBA)

16CholesterolIBA
06/2013 - 02/2002
3MucinsIBA
10/2010 - 02/2002
3Bile Acids and Salts (Bile Acids)IBA
10/2010 - 09/2003
2Phospholipids (Phosphatides)FDA LinkGeneric
05/2013 - 10/2010
2sodium-bile acid cotransporterIBA
11/2011 - 10/2009
2Proteins (Proteins, Gene)FDA Link
01/2010 - 10/2006
1Pharmaceutical PreparationsIBA
03/2016
1Budesonide (Pulmicort)FDA LinkGeneric
03/2016
1Bosentan (Tracleer)FDA Link
11/2014
1DNA (Deoxyribonucleic Acid)IBA
01/2012
1Carbon MonoxideIBA
01/2012
1Heme Oxygenase-1IBA
01/2012
1Heme (Haem)IBA
01/2012
1LipidsIBA
11/2011
1MicellesIBA
10/2010
1BilirubinIBA
10/2010
1CalciumIBA
10/2010
1Phytosterols (Plant Sterols)IBA
02/2010
1Peptide Hydrolases (Proteases)FDA Link
01/2010
1TrypsinogenIBA
01/2010
1SulfamethoxazoleFDA LinkGeneric
06/2008
1Trimethoprim (Proloprim)FDA LinkGeneric
06/2008
1Anti-Bacterial Agents (Antibiotics)IBA
06/2008
1HDL CholesterolIBA
08/2006
1lipoprotein cholesterolIBA
08/2006
1Messenger RNA (mRNA)IBA
08/2003
1Lipoproteins (Lipoprotein)IBA
05/2003
1Cholic AcidIBA
11/2002

Therapy/Procedure

3Cholecystectomy
05/2013 - 04/2005
1Proctectomy
11/2015
1Therapeutics
06/2008
1Enteral Nutrition (Feeding, Tube)
09/2006
1Gastrostomy
09/2006
1Lithotripsy (Extracorporeal Shockwave Lithotripsy)
04/2005
1Operative Surgical Procedures
04/2005